SEAFDECINSTITUTIONAL REPOSITORY
    • English
    • ไทย
    • 日本語
    • Bahasa Indonesia
    • Bahasa Melayu
    • Burmese
    • Filipino
    • Khmer
    • Lao
    • Tiếng Việt
  • English 
    • English
    • ไทย
    • 日本語
    • Bahasa Indonesia
    • Bahasa Melayu
    • Burmese
    • Filipino
    • Khmer
    • Lao
    • Tiếng Việt
  • Login
View Item 
  •   SEAFDEC Institutional Repository (SIR)
  • 03 SEAFDEC External Publications
  • Journal Articles, Conference Papers and Book Chapters by SEAFDEC Staff
  • Journal Articles
  • AQD Journal Articles
  • View Item
  •   SEAFDEC Institutional Repository (SIR)
  • 03 SEAFDEC External Publications
  • Journal Articles, Conference Papers and Book Chapters by SEAFDEC Staff
  • Journal Articles
  • AQD Journal Articles
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Immune responses of Asian sea bass, Lates calcarifer Bloch, against an inactivated betanodavirus vaccine

Thumbnail
View/Open
Request this document
Date
2009
Author
Pakingking, Rolando V., Jr.
Seron, R.
de la Peña, Leobert D.
Mori, K.
Yamashita, H.
Nakai, T.
Page views
143
Metadata
Show full item record

Cited times in Scopus



Share 
 
Abstract
Asian sea bass, Lates calcarifer (Bloch), exhibited strong immune responses against a single injection of the formalin-inactivated red-spotted grouper nervous necrosis virus (RGNNV), a betanodavirus originally isolated in Japan. Fish produced neutralizing antibodies at high titre levels from days 10 (mean titre 1:480) to 116 (1:1280), with the highest titre at day 60 post-vaccination (1:4480). When fish were challenged with the homologous RGNNV at day 54 post-vaccination, there were no mortalities in both the vaccinated and unvaccinated control fish. However, a rapid clearance of the virus was observed in the brains and kidneys of vaccinated fish, followed by a significant increase in neutralizing-antibody titres. Furthermore, the vaccine-induced antibodies potently neutralized Philippine betanodavirus isolates (RGNNV) in a cross-neutralization assay. The present results indicate the potential of the formalin-inactivated RGNNV vaccine against viral nervous necrosis (VNN) of Asian seabass.
URI
http://hdl.handle.net/10862/2098
Suggested Citation
Pakingking, R. V., Jr., Seron, R., de la Peña, L. D., Mori, K., Yamashita, H., & Nakai, T. (2009). Immune responses of Asian sea bass, Lates calcarifer Bloch, against an inactivated betanodavirus vaccine. Journal of Fish Diseases, 32(5), 457-463. https://doi.org/10.1111/j.1365-2761.2009.01040.x 
DOI
10.1111/j.1365-2761.2009.01040.x
Subject
marine fish ASFA; antibodies ASFA; fish diseases ASFA; viral diseases ASFA; disease control ASFA; vaccines ASFA; mortality causes ASFA; mortality ASFA; necrosis ASFA; brain ASFA; kidneys ASFA; vaccination ASFA; Dicentrarchus labrax AGROVOC; Lates calcarifer AGROVOC; Japan AGROVOC; Philippines AGROVOC
Taxonomic term
Lates calcarifer GBIF
Collections
  • AQD Journal Articles [1185]

Related items

Showing items related by title, author, creator and subject.

  • Thumbnail

    Immunization regimen in Asian sea bass (Lates calcarifer) broodfish: A practical strategy to control vertical transmission of nervous necrosis virus during seed production 

    Pakingking, Rolando V., Jr.; de Jesus-Ayson, Evelyn Grace; Reyes, Ofelia; Bautista, Norwell Brian (Elsevier, 2018-08)
    Outbreaks of viral nervous necrosis (VNN) in Asian sea bass (Lates calcarifer) at the larval stages via vertical transmission of nervous necrosis virus (NNV) from asymptomatic broodfish remain as a major deterrent during ...
  • Thumbnail

    Immunolocalisation of nervous necrosis virus indicates vertical transmission in hatchery produced Asian sea bass (Lates calcarifer Bloch)—A case study 

    Azad, I. S.; Jithendran, K. P.; Shekhar, M. S.; Thirunavukkarasu, A. R.; de la Pena, L. D. (Elsevier, 2006)
    A probable vertical mode of piscine nodavirus transmission is reported in the present investigation based on a case of nodavirus associated larval mortalities in hatchery produced Asian sea bass. Polyclonal rabbit anti-SJNNV ...
  • Thumbnail

    Vibrio harveyi isolated from cage-cultured seabass Lates calcarifer Bloch in the Philippines 

    Tendencia, Eleonor (Blackwell Publishing, 2002)

© SEAFDEC 2023
Contact Us
 

 

Browse

All of SIRCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

LoginRegister

Statistics

View Usage Statistics
Related Links
SEAFDEC/TD IRSEAFDEC/AQD IRSEAFDEC/MFRDMD IRSEAFDEC/IFRDMD IR

© SEAFDEC 2023
Contact Us